Wham clusters many of the prospect breakpoints and rounds their positions to the nearest tenth base pair. The position with the best go through support is described. If your smooth-clipped consensus sequence is usually aligned for the putative breakpoint location using the Smith-Waterman algorithm, the breakpoint is further more refined to the loca
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The delicate-clipped sequences that overhang the breakpoint are collapsed into a consensus sequence utilizing a a number of sequence alignment (MSA) provided from the seqAn library [27]. Wham applies a few filters to your consensus sequences. Breakpoints aren't reported in scenarios the place consensus sequences are shorter than 10 bp or include a